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ORIGINAL ARTICLE
Year : 2016  |  Volume : 4  |  Issue : 1  |  Page : 17-21

Efficacy studies on peracetic acid against pathogenic microorganisms


1 Department of Microbiology, Immunology and Molecular Biology, Choithram Hospital and Research Centre, Indore, Madhya Pradesh, India
2 Department of Microbiology, CHL Hospital, Indore, Madhya Pradesh, India
3 Department of Microbiology and Immunology, CHL Hospital, Indore, Madhya Pradesh, India

Correspondence Address:
Dhananjay Sadashiv Chitnis
Department of Microbiology, Immunology and Molecular Biology, Choithram Hospital and Research Centre, Manik Bagh Road, Indore - 452 014, Madhya Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2214-207X.203545

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Background: The peracetic acid (PAA) has antimicrobial activity against bacteria and fungi including spores and is envirosafe. Despite its widespread use in food industry and effluent treatment, it is not widely used in hospitals. The present work was aimed to find out its efficacy against hospital pathogens, bacterial and fungal spores and mycobacteria. Methods: Multidrug-resistant, wild hospital isolates of Gram-positive, Gram-negative bacteria, tough organisms such as Mycobacterium fortuitum, Mycobacterium tuberculosis and Candida albicans and spores of Bacillus subtilis, Clostridium perfringens and Aspergillus niger were checked by modified Kelsey-Sykes suspension test. For vegetative bacteria, exposure time was 1 min. For bacterial and fungal spores, Candida and Mycobacteria, exposure time varied from 10 to 30 min. Results: More than 5-log reduction was seen for vegetative bacteria just after 1 min exposure to PAA. Ten minute exposure to PAA could inactivate 99.5% bacterial and fungal spores. Mycobacteria were inactivated within 10 min of exposure to PAA. PAA rapidly inactivates pathogenic bacteria within 1 min and inactivates mycobacteria and fungi within 10 min and sterilises spores within 30 min and remains active in the presence of proteins. Conclusions: It is economic, eco-friendly and deserves major share in hospital disinfection.


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